The spleen represents the female aspect of judgments in Malchut. The bile is the aspect of male judgments in Malchut. The liver is male and represents the aspect of the exile of the soul at the levels of Neshama with its root in Binah from the levels of Ruach, Zeir Anpin, and Nefesh, which is the level of Malchut and the Shechina.
The soul seeks the light from the depth of the body, Malchut.
Jonah 2:3 “מִבֶּטֶן שְׁאוֹל שִׁוַּעְתִּי”
“…out of the belly of the dead I cried for salvation…”
In the final exile the Neshama will be ‘trapped’ in the Klipot.
Amos 5:2 “נָפְלָה לֹא-תוֹסִיף קוּם, בְּתוּלַת יִשְׂרָאֵל; נִטְּשָׁה עַל-אַדְמָתָהּ, אֵין מְקִימָהּ”
“The virgin of Israel (the pure soul) is fallen, she shall no more rise; she is cast down (to the Klipot) upon her land (Malchut), none (Endless = אין) to raise her up”
The Zohar says, woe to the person that his soul becomes trapped in the Klipot at the time of the final redemption. Only with the power of the holy name, the soul can break free from the bondage of the Klipot.